Fructose-1, 6-bisphosphatase is activated in response to a glucagon signal.
What is the purpose of Glucagon signals?
Glucagon signals specify that fuel molecules are required in the bloodstream.
So these signals activate Fructose-1, 6-bisphosphatase (F1, 6BP) so as to increase the level of sugar and other fuels required for production of energy.
In the process of gluconeogenesis, new glucose molecules are synthesized from other non carbohydrate sources.
As glucose is required in the bloodstream so F-1, 6BP should be activated as it acts as a rate limiting enzyme in gluconeogenesis.
Gluconeogenesis occurs when the dietary intake of glucose is very low.
Glucose is required as a source of energy by almost all body cells so in case of less oxygen it is synthesized from other molecules like amino acids.
